Hospital Efficiency: An Empirical Analysis of District and Grant-in-Aid Hospitals in Gujarat

This study focuses on analysing the hospital efficiency of district level government hospitals and grant-in-aid hospitals in Gujarat. The study makes an attempt to provide an overview of the general status of the health care services provided by hospitals in the state of Gujarat in terms of their technical and allocative efficiency. One of the two thrusts behind addressing the issue of efficiency was to take stock of the state of healthcare services (in terms of efficiency) provided by grant-in-aid hospitals and district hospitals in Gujarat. The motivation behind addressing the efficiency issue is to provide empirical analysis of governments policy to provide grants to not-for-profit making institutions which in turn provide hospital care in the state. The study addresses the issue whether grant-in-aid hospitals are relatively more efficient than public hospitals. This comparison between grant-in-aid hospitals and district hospitals in terms of their efficiency has been of interest to many researchers in countries other than India, and no consensus has been reached so far as to which category is more efficient. The relative efficiency of government and not-for-profit sector has been reviewed in this paper. It is expected that the findings of the study would be useful to evaluate this policy and help policy makers to develop benchmarks in providing the grants to such institutions.

An Investigation paper on Congestion Control Policy

In the advancement of network technology traffic affects performance factors like file synchronization, communication throughput and overall all the scenario where one are having continues connectivity of business to the rectifying organizations, all the business functionality are going for the achievement of paperless communication infrastructure where one are deploying all his working by the internet technology such high speed network communication infrastructure always required well suited congestion less architecture scheme to achieve quality of services ,In the field of different communication area there are many applications has be running at present for all type of users likesenior, junior and all business users categories. Network proposed many protocols and algorithm for the improvement in flow of the network,Ethernet project 802 and protocols series 802.11a/b/c/d/e has been working at network layer in which user’s found some times network work well with priorities choice of network connection but sometimesstruggles with the same.To analyze the actual report of congestion policies here author of the paper are presenting analytical study so that one can understand the lack of functionality in communication with specific network implementations

Disturbance of oxidant/antioxidant balance, acute phase response and high mobility group box–1 protein in acute undifferentiated diarrhea in crossbred piglets

The objective of the present study was to investigate the status of high mobility group box–1 (HMGB1) protein, oxidative stress and acute phase proteins in natural cases of acute undifferentiated diarrhoea in piglets aged 1–15 days old. The study was conducted on 30 crossbred (Landrace × indigenous) piglets; fifteen suffering from acute enteritis (group 1) and fifteen healthy piglets as control (group 2). The diarrhoea was diagnosed on the basis of clinical symptoms. From the results of the study, it is concluded that HMGB1 protein, markers of oxidative stress and acute phase proteins might play important roles in the pathophysiology of piglet diarrhoea and that these may be targets for supportive therapy

Incidence of Piriformis Tightness and to determine correlation with gluteus medius weakness in Indian IT – Professionals: A cross sectional study

Background: The usage of computers is rising in every field of work, mainly in IT professionals where a professional sit in a computer for long period of time. This increases the prevalence of musculoskeletal disorders, like low back pain and neck pain. Continues sitting for long period of time can cause tightness in piriformis muscle and can lead to piriformis syndrome and it can also affect the other hip muscles to become weak, and ultimately it can cause low back pain. Weak Gluteus Medius muscle was also found in the peoples suffering from low back pain and continues sitting. This study aims to identify the incidences of piriformis muscle tightness and to determine correlation with gluteus medius weakness. This study is based on an observational based design, 100 IT professionals were taken randomly. Method: IT professionals (n=100) registered during this study & on the basis of inclusion & exclusion criteria they are evaluated. The collected data is obtained by performing piriformis stretch test for checking tightness of piriformis & Manual muscle testing of Glutes Medius. Result: Out of 100 subjects 68% of the subjects are clinically diagnosed with piriformis muscle tightness & 37% subjects are having weak gluteus medius muscle.&nbsp

A Critical Review on the Scope of Management of Academic Stress in Adolescents with Sattvavajaya Chikitsa (Ayurved Psychotherapy)

The adolescent stage of life is unique having various physical and psychological changes occurring in the body and in the brain. Academic stress (AS) is largely responsible for adolescents developing mental illnesses. A competitive environment, the pursuit of high scores in marks, peer comparisons, and parental expectations are the most common stressors for an adolescent to develop AS. Early identification of the stressed person, his sensitivity toward stress, and appropriate stress coping can help a person to develop the strength for coping with various stressful situations. Reports and articles published online from the year 1995 to 2022 were taken into account among them 95 articles were identified of which 25 articles had abstracts only were excluded and 70 articles including textbook references were reviewed and discussed. Ayurveda has the unique concept of Prakriti (~somatic constitution) helps a person to recognize himself and to realize his strengths and weaknesses, through which one can ignore or manage stressful situations. This stress coping can be more emphasized with the practice of Sattvavajaya Chikitsa(~Ayurvedic psychotherapy). Sattvavajaya Chikitsa works based on Manonigraha (control of the mind). Sadvrittta (~code of conduct for mental health), Swasthavritta (~measure to uplift general health), Achar Rasayana (~Ayurved code of conduct), Yoga, Surya Namaskar (~sun salutation), and meditation are different ways to practice mindfulness. Proper practice of Manonigraha (~control of mind) creates a connection between the mind, psyche, and body. The long-term practice of Manonighraha helps an academically stressed individual to better cope with stress and has finer mental and physical health.

Differential response of immune-related genes to peptidoglycan and lipoteichoic acid challenge in vitro

Aim: To study the effect of Staphylococcus aureus cell wall antigens, peptidoglycan (PGN) and lipoteichoic acid (LTA) challenge on immune cells present in bovine peripheral blood mononuclear cells (PBMCs). Materials and Methods: In this study, efforts have been made to investigate the effects of three combinations (10+10, 20+20 and 30+30 μg/ml) of PGN and LTA obtained from S. aureus. These antigens were used to challenge the bovine PBMCs. After 6 h of incubation quantitative, real time-polymerase chain reaction was used to study toll-like receptor 2 (TLR-2) and major cytokine mRNA expression in bovine PBMC challenged with three different antigen blends. Results: The results indicated that mRNA level of interferon gamma is influenced by the expression of TLR-2 gene. Tumor necrosis factor-alpha (TNF-α), interleukin 10 (IL-10), and IL-8 genes showed a maximum response at a dose of 10 μg of PGN and 10 μg of LTA challenge per ml of culture medium. The outcome also suggests that both IL-10 and IL-8 followed the expression pattern of TNF-α. Conclusion: A dose of 10 μg of PGN and 10 μg of LTA per ml of culture medium was found to be most suitable for challenging PBMC

Characterization of difference in structure and function of fresh and mastitic bovine milk fat globules.

Characterization of milk fat globule (MFG) was performed to investigate the difference in MFG membrane (MFGM) between fresh and mastitis Holstein Friesian cow milk. Lipid distribution investigated by exogenous phospholipids using microscopy showed higher phospholipid content in fresh compared to mastitic MFGM. Xanthine oxidase assay indicative of membrane impairment revealed lower activity in mastitic samples compared to fresh globules. Of note, significantly higher roughness of globule surface and zeta potential was observed in mastitis compared to fresh globules. Influence of globule membrane on the interaction with L. fermentum demonstrated preferential adhesion of bacteria to fresh compared to mastitic globules including enhanced extent of binding. Results of the present study provides an insight of the interfacial changes occurring at the globule surface as well as highlighting the importance of selective bacterial interaction with milk components for the potential development of functional food with relevance to human health

<i>Game-o-Meta</i>: Trusted Federated Learning Scheme for P2P Gaming Metaverse beyond 5G Networks

The aim of the peer-to-peer (P2P) decentralized gaming industry has shifted towards realistic gaming environment (GE) support for game players (GPs). Recent innovations in the metaverse have motivated the gaming industry to look beyond augmented reality and virtual reality engines, which improve the reality of virtual game worlds. In gaming metaverses (GMs), GPs can play, socialize, and trade virtual objects in the GE. On game servers (GSs), the collected GM data are analyzed by artificial intelligence models to personalize the GE according to the GP. However, communication with GSs suffers from high-end latency, bandwidth concerns, and issues regarding the security and privacy of GP data, which pose a severe threat to the emerging GM landscape. Thus, we proposed a scheme, Game-o-Meta, that integrates federated learning in the GE, with GP data being trained on local devices only. We envisioned the GE over a sixth-generation tactile internet service to address the bandwidth and latency issues and assure real-time haptic control. In the GM, the GP’s game tasks are collected and trained on the GS, and then a pre-trained model is downloaded by the GP, which is trained using local data. The proposed scheme was compared against traditional schemes based on parameters such as GP task offloading, GP avatar rendering latency, and GS availability. The results indicated the viability of the proposed scheme

Relative expression of oxytocin receptor gene in buffalo endometrium in late luteal phase and pregnancy stages

Molecular level information related to buffalo (Bubalus bubalis) reproduction and related genes is not present at appropriate level. If such exploration is made in the form of comparison between expression of genes is made between non-pregnant and pregnant phase, it may be helpful to aid manipulate the reproduction. Hence, the present study was carried out to reveal mRNA quantitative real time expression of oxytocin receptor (OTR) mRNA. IFN-τ is considered as the substance of maternal recognition of pregnancy and shut down the probable mechanisms which lead to luteolysis. Such mechanism includes shutting down of OTR. Therefore, relative expression of OTR was studied in endometrial tissue of three groups. The groups were non-pregnant late luteal phase, pregnancy stage I (pregnancy of 42 days of pregnancy). With designed primer and GAPDH as house-keeping gene, relative mRNA expression was measured in Real-time PCR. After statistical analysis of results, the gene found to be expressed in all three stages with non-significant difference

Differential cytokine response of Escherichia coli lipopolysaccharide stimulated peripheral blood mononuclear cells in crossbred cattle, Tharparkar cattle and Murrah buffalo - An in vitro study

Mastitis is a complex disease responsible for huge economic losses to the dairy sector. The causal organisms include a wide variety of micro-organisms including several species of bacteria. Escherichia coli has been identified as one of the most common gram-negative bacteria causing clinical mastitis in cattle. The immune system, of different species and/or breeds, tries to combat these pathogens in an inconsistent manner with differential mode and intensity of immune response, eventually producing contradicting outcomes of this disease. Several reports suggest the existence of variability among different animal breeds/species, resulting in a dissimilar outcome of this disease among them. In order to evaluate the variation among different breeds/species, the present study was undertaken to examine the stimulant effect of E. coli lipopolysaccharide (LPS) on peripheral blood mononuclear cells (PBMCs). The PBMCs were harvested from blood samples of crossbred cattle, Tharparkar cattle and Murrah buffaloes. After 6 h of in vitro stimulation, qRT-PCR was employed to measure the relative mRNA expression levels of CCL5, IL-1β, IL-12β, IFN-γ and IL-10 genes in stimulated and unstimulated PBMCs. The selected genes revealed significant differences in the pattern of innate immune response among crossbred cattle, Tharparkar cattle and Murrah buffaloes. The results clearly indicate the presence of variation in the outcome of immune response even when the immunocytes were stimulated with the same dose of the antigen